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1

Targeting a dark excited state of HIV-1 nucleocapsid by anti-retroviral thioesters revealed by NMR

Deshmukh, Lalit, Tugarinov, Vitali, Appella, Daniel H., Clore, G. Marius

Journal:

Angewandte Chemie International Edition

Year:

2018

Language:

english

File:

PDF, 1.06 MB

english, 2018

2

Quantification of plasma HIV RNA using chemically engineered peptide nucleic acids

Zhao, Chao, Hoppe, Travis, Setty, Mohan Kumar Haleyur Giri, Murray, Danielle, Chun, Tae-Wook, Hewlett, Indira, Appella, Daniel H.

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

3

Synthesis and Structural Characterization of Helix-Forming β-Peptides: trans -2-Aminocyclopentanecarboxylic Acid Oligomers

Appella, Daniel H., Christianson, Laurie A., Klein, Daniel A., Richards, Michele R., Powell, Douglas R., Gellman, Samuel H.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 351 KB

english, 1999

4

Synthesis and Characterization of trans -2-Aminocyclohexanecarboxylic Acid Oligomers: An Unnatural Helical Secondary Structure and Implications for β-Peptide Tertiary Structure

Appella, Daniel H., Christianson, Laurie A., Karle, Isabella L., Powell, Douglas R., Gellman, Samuel H.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 237 KB

english, 1999

5

Non-natural nucleic acids for synthetic biology

Daniel H Appella

Journal:

Current Opinion in Chemical Biology

Year:

2009

Language:

english

File:

PDF, 471 KB

english, 2009

6

Asymmetric Conjugate Reduction of α,β-Unsaturated Esters Using a Chiral Phosphine−Copper Catalyst

Appella, Daniel H., Moritani, Yasunori, Shintani, Ryo, Ferreira, Eric M., Buchwald, Stephen L.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 71 KB

english, 1999

7

Colorimetric Detection of Anthrax DNA with a Peptide Nucleic Acid Sandwich-Hybridization Assay

Zhang, Ning, Appella, Daniel H.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 85 KB

english, 2007

8

Targeting a dark excited state of HIV-1 nucleocapsid by anti-retroviral thioesters revealed by NMR

Deshmukh, Lalit, Tugarinov, Vitali, Appella, Daniel H., Clore, G. Marius

Journal:

Angewandte Chemie

Year:

2018

Language:

english

File:

PDF, 1.06 MB

english, 2018

9

Synthesis of β-Alkyl Cyclopentanones in High Enantiomeric Excess via Copper-Catalyzed Asymmetric Conjugate Reduction

Moritani, Yasunori, Appella, Daniel H., Jurkauskas, Valdas, Buchwald, Stephen L.

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 93 KB

english, 2000

10

PNA−DNA Duplexes, Triplexes, and Quadruplexes Are Stabilized with trans- Cyclopentane Units

Englund, Ethan A., Xu, Qun, Witschi, Mark A., Appella, Daniel H.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 45 KB

english, 2006

11

Correction to Click Dimers To Target HIV TAR RNA Conformation

Kumar, Sunil, Kellish, Patrick, Robinson, W. Edward, Wang, Deyun, Appella, Daniel H., Arya, Dev P.

Journal:

Year:

2013

File:

PDF, 213 KB

2013

12

Two Types of Lambda Polypeptide Chains in Human Immunoglobulins Based on an Amino Acid Substitution at Position 190

Ettore Appella and Daniel Ein

Journal:

Proceedings of the National Academy of Sciences

Year:

1967

Language:

english

File:

PDF, 732 KB

english, 1967

13

Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

Pokorski, Jonathan K., Nam, Jwa-Min, Vega, Rafael A., Mirkin, Chad A., Appella, Daniel H.

Journal:

Chemical Communications

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

14

Practical Synthesis of trans - tert -Butyl-2-aminocyclopentylcarbamate and Resolution of Enantiomers

Xu, Qun, Appella, Daniel H.

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 50 KB

english, 2006

15

Asymmetric Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with a Cationic Zirconocene Catalyst

Troutman, Malisa V., Appella, Daniel H., Buchwald, Stephen L.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 38 KB

english, 1999

16

Enhanced Oligonucleotide Binding to Self-Assembled Nanofibers

Guler, Mustafa O., Pokorski, Jonathan K., Appella, Daniel H., Stupp, Samuel I.

Journal:

Bioconjugate Chemistry

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

17

Synthesis of Fmoc-Protected ( S , S )- trans -Cyclopentane Diamine Monomers Enables the Preparation and Study of Conformationally Restricted Peptide Nucleic Acids

Zheng, Hongchao, Saha, Mrinmoy, Appella, Daniel H.

Journal:

Organic Letters

Year:

2018

Language:

english

File:

PDF, 589 KB

english, 2018

18

γ-Substituted Peptide Nucleic Acids Constructed from L-Lysine are a Versatile Scaffold for Multifunctional Display

Ethan A. Englund, Daniel H. Appella

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 436 KB

english, 2007

19

ChemInform Abstract: Synthesis and Structural Characterization of Helix-Forming β-Peptides: trans-2-Aminocyclopentanecarboxylic Acid Oligomers.

Daniel H. Appella, Laurie A. Christianson, Daniel A. Klein, Michele R. Richards, Douglas R. Powell, Samuel H. Gellman

Journal:

Year:

1999

File:

PDF, 27 KB

1999

20

ChemInform Abstract: Asymmetric Conjugate Reduction of α,β-Unsaturated Esters Using a Chiral Phosphine—Copper Catalyst.

Daniel H. Appella, Yasunori Moritani, Ryo Shintani, Eric M. Ferreira, Stephen L. Buchwald

Journal:

Year:

2000

File:

PDF, 31 KB

2000

21

A Small Molecular Scaffold for Selective Inhibition of Wip1 Phosphatase

Jeong Bang, Hiroshi Yamaguchi, Stewart R. Durell, Ettore Appella, Daniel H. Appella

Journal:

Year:

2008

Language:

english

File:

PDF, 357 KB

english, 2008

22

Solid-phase synthesis and screening of N-acylated polyamine (NAPA) combinatorial libraries for protein binding

Jaclyn A. Iera, Lisa M. Miller Jenkins, Hiroshi Kajiyama, Jeffrey B. Kopp, Daniel H. Appella

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 496 KB

english, 2010

23

Peptide Nucleic Acids with a Flexible Secondary Amine in the Backbone Maintain Oligonucleotide Binding Affinity

Myers, Michael C., Pokorski, Jonathan K., Appella, Daniel H.

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 127 KB

english, 2004

24

Nonionic Side Chains Modulate the Affinity and Specificity of Binding between Functionalized Polyamines and Structured RNA

Lawton, Graham R., Appella, Daniel H.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 72 KB

english, 2004

25

PNA Clamping in Nucleic Acid Amplification Protocols to Detect Single Nucleotide Mutations Related to Cancer

Fouz, Munira F., Appella, Daniel H.

Journal:

Year:

2020

Language:

english

File:

PDF, 593 KB

english, 2020

26

[Methods in Molecular Biology] Peptide Nucleic Acids Volume 1050 ||

Nielsen, Peter E, Appella, Daniel H.

Year:

2014

Language:

english

File:

PDF, 4.95 MB

english, 2014

27

Photoinduced Cycloaddition and Ene Reactions of 2,7-Cyclooctadienone: Experimental and Computational Studies of a Cyclopentyl Oxyallyl Intermediate

Matlin, Albert R., Lahti, Paul M., Appella, Daniel, Straumanis, Andrei, Lin, Susanne, Patel, Hiren, Jin, Kyo, Schrieber, Keith P., Pauls, Jonathan, Raulerson, Patrick

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 216 KB

english, 1999

28

A one-pot preparation of N-2-mercaptobenzoyl-amino amides

Robert J. Bahde, Daniel H. Appella, William C. Trenkle

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 211 KB

english, 2011

29

Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen

Simister, Philip C., Luccarelli, James, Thompson, Sam, Appella, Daniel H., Feller, Stephan M., Hamilton, Andrew D.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

30

Directed evolution: Overcoming biology's limitations

Appella, Daniel H

Journal:

Nature Chemical Biology

Year:

2010

Language:

english

File:

PDF, 159 KB

english, 2010

31

Probing the Structural Requirements of Peptoids That Inhibit HDM2−p53 Interactions

Hara, Toshiaki, Durell, Stewart R., Myers, Michael C., Appella, Daniel H.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 591 KB

english, 2006

32

PPG Peptide Nucleic Acids that Promote DNA Guanine Quadruplexes

Englund, Ethan A., Gupta, Pankaj, Micklitsch, Christopher M., Onyshchenko, Mykola I., Remeeva, Evgenia, Neumann, Ronald D., Panyutin, Igor G., Appella, Daniel H.

Journal:

Year:

2014

Language:

english

File:

PDF, 551 KB

english, 2014

33

An Efficient Synthesis of a Probe for Protein Function: 2,3-Diaminopropionic Acid with Orthogonal Protecting Groups

Englund, Ethan A., Gopi, Hosahudya N., Appella, Daniel H.

Journal:

Organic Letters

Year:

2004

File:

PDF, 5 KB

2004

34

ChemInform Abstract: Synthesis of β-Alkyl Cyclopentanones in High Enantiomeric Excess via Copper-Catalyzed Asymmetric Conjugate Reduction.

Yasunori Moritani, Daniel H. Appella, Valdas Jurkauskas, Stephen L. Buchwald

Journal:

Year:

2000

File:

PDF, 35 KB

2000

35

Improved treatment of cyclic ?-amino acids and successful prediction of ?-peptide secondary structure using a modified force field: AMBER*C

Christianson, Laurie A., Lucero, Melissa J., Appella, Daniel H., Klein, Daniel A., Gellman, Samuel H.

Journal:

Journal of Computational Chemistry

Year:

2000

Language:

english

File:

PDF, 288 KB

english, 2000

36

Targeting DNA G-Quadruplex Structures with Peptide Nucleic Acids

G. Panyutin, Igor, I. Onyshchenko, Mykola, A. Englund, Ethan, H. Appella, Daniel, D. Neumann, Ronald

Journal:

Current Pharmaceutical Design

Year:

2012

Language:

english

File:

PDF, 420 KB

english, 2012

37

Recognition of HIV-TAR RNA using neomycin–benzimidazole conjugates

Ranjan, Nihar, Kumar, Sunil, Watkins, Derrick, Wang, Deyun, Appella, Daniel H., Arya, Dev P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 894 KB

english, 2013

38

A New Family of Small Molecules To Probe the Reactivation of Mutant p53

Myers, Michael C., Wang,, Iera, Jaclyn A., Bang, Jeong-kyu, Hara, Toshiaki, Saito, Shin'ichi, Zambetti, Gerard P., Appella, Daniel H.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 102 KB

english, 2005

39

A Cyclopentane Conformational Restraint for a Peptide Nucleic Acid: Design, Asymmetric Synthesis, and Improved Binding Affinity to DNA and RNA

Myers, Michael C., Witschi, Mark A., Larionova, Nataliya V., Franck, John M., Haynes, Russell D., Hara, Toshiaki, Grajkowski, Andrzej, Appella, Daniel H.

Journal:

Organic Letters

Year:

2003

Language:

english

File:

PDF, 68 KB

english, 2003

40

Reaction Kinetics Direct a Rational Synthesis of an HIV-1 Inactivator of Nucleocapsid Protein 7 and Provide Mechanistic Insight into Cellular Metabolism and Antiviral Activity

Nikolayevskiy, Herman, Scerba, Michael T., Deschamps, Jeffrey R., Appella, Daniel H.

Journal:

Chemistry - A European Journal

Year:

2018

Language:

english

File:

PDF, 1.43 MB

english, 2018

41

Aziridination of Aliphatic Alkenes Catalyzed by N -Heterocyclic Carbene Copper Complexes

Xu, Qun, Appella, Daniel H.

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 73 KB

english, 2008

42

Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA

Pokorski, Jonathan K., Appella, Daniel H.

Journal:

Journal of Nucleic Acids

Year:

2012

Language:

english

File:

PDF, 1.61 MB

english, 2012

43

Degenerate Cytotoxic T Cell Epitopes from P. falciparum Restricted by Multiple HLA-A and HLA-B Supertype Alleles

Denise L Doolan, Stephen L Hoffman, Scott Southwood, Peggy A Wentworth, John Sidney, Robert W Chesnut, Elissa Keogh, Ettore Appella, Thomas B Nutman, Altaf A Lal, Daniel M Gordon, Aggrey Oloo, Alessan

Journal:

Year:

1997

Language:

english

File:

PDF, 203 KB

english, 1997

44

Programmable Nanoscaffolds That Control Ligand Display to a G-Protein-Coupled Receptor in Membranes To Allow Dissection of Multivalent Effects

Dix, Andrew V., Moss, Steven M., Phan, Khai, Hoppe, Travis, Paoletta, Silvia, Kozma, Eszter, Gao, Zhan-Guo, Durell, Stewart R., Jacobson, Kenneth A., Appella, Daniel H.

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 2.84 MB

english, 2014

45

ChemInform Abstract: Asymmetric Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with a Cationic Zirconocene Catalyst.

Malisa V. Troutman, Daniel H. Appella, Stephen L. Buchwald

Journal:

Year:

1999

File:

PDF, 35 KB

1999

46

A trapped human PPM1A–phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity

Debnath, Subrata, Kosek, Dalibor, Tagad, Harichandra D, Durell, Stewart R, Appella, Daniel H, Acevedo, Roderico, Grishaev, Alexander, Dyda, Fred, Appella, Ettore, Mazur, Sharlyn J.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 864 KB

english, 2018

47

Residue-based control of helix shape in β-peptide oligomers

Appella, Daniel H., Christianson, Laurie A., Klein, Daniel A., Powell, Douglas R., Huang, Xiaolin, Barchi, Joseph J., Gellman, Samuel H.

Journal:

Year:

1997

File:

PDF, 1.02 MB

1997

48

γ-Substituted Peptide Nucleic Acids Constructed from L-Lysine are a Versatile Scaffold for Multifunctional Display

Ethan A. Englund, Daniel H. Appella

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 437 KB

english, 2007

49

Books in Review - Proteomics: Biomedical and Pharmaceutical Applications | Proteomics Today: Protein Assessment and Biomarkers Using Mass Spectrometry, 2D Electrophoresis,and Microarray Technology

Smith, Jeffrey C., Figeys, Daniel, Appella, Ettore

Journal:

Journal of Proteome Research

Year:

2005

Language:

english

File:

PDF, 59 KB

english, 2005

50

An Efficient Synthesis of a Probe for Protein Function: 2,3-Diaminopropionic Acid with Orthogonal Protecting Groups

Englund, Ethan A., Gopi, Hosahudya N., Appella, Daniel H.

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 64 KB

english, 2004

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